Colorectal and Peritoneal Oncology Annual Service Report 2021 - 2022

Service Report 2022 Colorectal and Peritoneal Oncology Centre – The Christie NHS Foundation Trust

6.7 Complications

Complications Appendix/PMP (2021-2022)

n

%

No Complications

71 83 10

42.77% 50.00%

Minor Complications (NCI grade 1 - 2) Major Complications (NCI grade 3 - 4) Peri-Operative (30 Day) Mortality Peri-Operative (0-90 Day) Mortality

6.02% 1.20% 0.00%

2 0

Complications CRPM (2021-2022)

n

%

No Complications

39 41

43.82% 46.07% 10.11%

Minor Complications (NCI grade 1 - 2) Major Complications (NCI grade 3 - 4) Peri-Operative (30 Day) Mortality Peri-Operative (0-90 Day) Mortality

9 0 0

0.00% 0.00%

Minimal Access Laparoscopic Cytoreduction & HIPEC Complications (n=82)

n

%

No Complications

63 14

76.83 17.07

Minor Complications (NCI grade 1 - 2) Major Complications (NCI grade 3 - 4)

5 0 0

6.10 0.00 0.00

Peri Operative (30 Day) Death Peri Operative (90 Day) Death

Complication rates overview for Cytoreduction & HIPEC/Debulk procedures

Peri-Operative (30 Day) Mortality

Peri-Operative (90 Day) Mortality

Minor Complications*

Major Complications**

Cases

n 9

%

n

%

n 0 0 1 1 0 0 1 0 0 1 2

% n 0.00% 0 0.00% 0 0.99% 1 0.66% 1 0.00% 2 0.00% 2 0.56% 1 0.00% 1 0.00% 1 0.53% 1 1.00% 0 0.35% 10

%

2011-2012 2012-2013 2013-2014 2014-2015 2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 2020-2021 2021-2022

81 89

11.11% 22.47% 22.77% 28.48% 25.32% 19.57% 32.40% 25.71% 23.44% 29.25% 33.30% 25.91%

18 12 17 16 31 27 13 28 23 26 18

22.22% 13.48% 16.83% 10.60% 19.62% 14.67% 16.00% 11.98% 13.82% 7.26%

0.00% 0.00% 0.99% 0.66% 1.26% 1.09% 0.56% 0.57% 0.52% 0.53% 0.00% 0.59%

20 23 43 40 36 58 45 45 55 65

101 151 159 184 179 175 192 188 195

9.20%

Total

1,694

439

229

13.52% 6

*Defined as Grade 1 or 2 NCI Common Terminology Criteria for Adverse Events (v4.0) **Defined as Grade 3 or 4 NCI Common Terminology Criteria for Adverse Events (v4.0)

Grade 1 Mild; asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated. Grade 2 Moderate; minimal, local or non-invasive intervention indicated; limiting age-appropriate instrumental activities of daily living. Grade 3: Severe or medically significant but not immediately life-threatening; hospitalization or prolongation of hospitalisation indicated; disabling; limiting self-care activities of daily living. Grade 4: Life-threatening consequences; urgent intervention indicated. Grade 5: Death related to AE.

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